Oxytocin exerts broad range of central and peripheral effects. As a neurotransmitter it has effects on sexual function, intimacy, maternal bounding, feeding behavior, and social memory .It plays vital role in both arousal and ejaculation. Despite its extensive involvement in social and sexual aspects it represent under exploited area in sexology.
An electronic search was made, using different database websites.Key words used were oxytocin, erectile function, premature ejaculation oxytonic agonist and antagonist. It was followed by study of pharmacological effects factor effecting its release and functioning.
Search revealed that oxytocin has variable functions as neurotransmitter and hormone. Oxytonic receptors can be manipulated to produce variable psychosexual effects .It plays more pronounced role in females.
Oxytocin is generally known as love hormone. As it has affects on social, sensual, and sexual aspects of love. It enhances human social recognition, promotes intimacy and trust. Stimulation of oxytonic receptors in PVN of hypothalamus induces erection. It modulates androgen level by converting testosterone into dihydrotestosterone. It improves contractility of seminiferious tubules ,epididymis and prostate gland to aid sperm release. . Finally role played in childbirth, maternal bounding and milk secretion make it cardinally important in preservation of human specie. Certain social behaviors and manipulation of erogenous zone improve its secretion .MDMA improves and SSRI, s decrease its secretion. Intranasal OT can be used for treatment of anorgasmia and retarded ejaculation.
Oxytocin and its receptor has potential to be utilized in number of sexual and reproductive disorders.